Healthcare Transformation Lab

The Healthcare Transformation Lab at Lab at Massachusetts General Hospital’s mission is to improve the experience and value of health care through collaborative innovation in care processes and digital technologies.

Located in Boston, a hub of leading teaching hospitals, start-ups, academia and technology, the HTL sits within Massachusetts General Hospital. The HTL works to support, connect and inspire passionate people fom diverse backgrounds as they collaborrate on ways to improve healthcare.

Featured Staff

Eric Isselbacher, MD MHCDS

Founder & Director

Jared Conley, MD PhD MPH

Associate Director

Amy Dickey, MD

Pulmonary Critical Care Faculty, HTL Health care Innovation Fellow

Eric Isselbacher is cardiologist at Mass General Hospital and Associate Professor of Medicine Harvard Medical School. He is committed to seeing significant improvements in health care and has helped oversee numerous innovative projects at HTL that have had great impact at MGH and beyond.  He is a graduate of Harvard College and Harvard Medical School and completed both his medical residency and cardiology fellowship at Mass General Hospital.

Jared Conley is an emergency physician and innovator at Mass General Hospital and Harvard Medical School.  He is dedicated to working with others in leading a revolution in care by employing the science of innovation and the enabling power of digital technologies. He completed a joint MD/PhD program at Case Western School of Medicine with an emphasis on health care organization and policy, as well as received a MPH from The Dartmouth Institute. His clinical training was obtained at Harvard (MGH/BWH) and he completed a fellowship in health care delivery innovation at Stanford University.

Amy Dickey is a Healthcare Transformation Lab Fellow in Healthcare Innovation and an Instructor in the Pulmonary and Critical Care Division of the Mass General Department of Medicine. She is passionate about adapting and applying technologies for use in porphyria, a family of genetic diseases affecting the production of heme. Her innovation project focuses on developing and applying digital health technologies to assist in the diagnosis and treatment of porphyria.

Program Priorities

Innovation Accelerator

Clinician Innovator Incubator

Technology Curator

Accelerating the work of technology-enabled, higher-value care through collaborative innovation with clinicians, startups, payers, and other stakeholders

Enhancing clinician skillset/experience in health care delivery innovation:

  1. Applied Research Fellowship in Health care Innovation
  2. Health care Innovation Elective
  3. Housestaff Program in Health care Innovation

Serving as a resource for both clinicians and startups to better link front-line health care pain points with the best tech solutions

Programmatic Highlights

Cost to Cath

Project winner of the inaugural 2014 Ether Dome Challenge in the MGH Heart Center. Meg McCleary and David Bourque dedicated significant time and energy to understanding, analyzing, and reducing unnecessary use of supplies in the Cath Lab. As a result of this project and its spinoffs, if all recommended changes are adhered to, the potential projected cost savings for the hospital was $1 million annually. Since the completion of the project 3 years ago, the team has been implementing creative strategies to engage staff and have become ambassadors for using collaborative innovation to optimize value.


Dr. Areej El-Jawahri and her team care for patients with Acute Myeloid Leukemia and saw an urgent need to bridge inpatient psych support resources with an intervention that could both teach patients about their diagnosis while simultaneously conveying basic cognitive behavioral therapy techniques to manage their stress. A year and a half later, an iPad game titled DreAMLand, is halfway through a multi-site control trial and is being submitted for FDA approval as a digital therapeutic.


For the inaugural cohort of MassChallenge HealthTech (previously PULSE @ MassChallenge), HTL matched with a startup called Medumo, which was working with Dr. James Richter and Emily Campbell in gastroenterology to put together a pilot to reduce failed colonoscopy prep via automated reminders that would be texted to patients. In the year since HTL completed work with Medumo, Mass General Brigham signed on for an enterprise rollout, and gastroenterology completed an extended yearlong pilot with plans to scale. Medumo was acquired by Philips in summer 2019.